The Nicotine Effect

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The 'nicotine effect':

      Nicotine acts as both a stimulant and a sedative. When a body is exposed to nicotine, the individual experiences a "kick." This is partly caused by nicotine stimulating the adrenal glands, which results in the release of adrenaline.
      This surge of adrenaline stimulates the body. There is an immediate release of glucose in blood(slight hyperglycemic), as well as an increase in heart rate, breathing activity, and blood pressure.Nicotine also makes the pancreas produce less insulin(which regulates the blood glucose concentration), causing a slight increase in blood sugar or glucose.This is how nicotine curbs the Appetite.

    Indirectly, nicotine causes the release of dopamine in the pleasure and motivation areas of the brain. A similar effect occurs when people take heroin or cocaine. The drug user experiences a pleasurable sensation.
    Dopamine is a brain chemical that affects emotions, movements, and sensations of pleasure and pain. If your brain dopamine levels rise, the feeling of contentment is higher.This leads to addiction of tobacco.Depending on the dose of nicotine taken and the individual's nervous system arousal, nicotine can also act as a sedative.
     Repeated exposure to nicotine results in the development of tolerance, the condition in which higher doses of a drug are required to produce the same initial effect. Nicotine is metabolized fairly rapidly, disappearing from the body in a few hours. Therefore some tolerance is lost overnight and smokers often report that the first cigarettes of the day are the strongest and/or the "best." Tolerance progresses as the day develops, and later cigarettes have less effect.
    

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